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You asked:What disease is mirtazapine predominantly used for
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[mirtazapine]
  • Serotonin-potentiating non-SSRIs, such as venlafaxine, nefazodone, trazodone and mirtazapine, have been evaluated in PTSD only in open-label and case studies..[Gregory:2004]{Human,Guideline}

[predominantly]
  • Bupropion (amfebutamone), a predominantly noradrenergic reuptake inhibitor, was ineffective in PTSD in an open-label study..[Gregory:2004]{Human,Guideline}

[disorder]
  • Post-traumatic stress disorder (PTSD) is a highly prevalent (7.8% lifetime rate) anxiety disorder with impairment in daily functioning, frequent suicidal behaviour and high rates of co-morbidity..[Gregory:2004]{Human,Guideline}

[used]
  • They should be avoided or used only short term because of potential depressogenic effects, and the possibility that they may promote or worsen PTSD..[Gregory:2004]{Human,Guideline}