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Query : Which enzyme is involved in the maintenance of DNA (cytosine-5-)-methylation?, reformulated as enzym involv mainten cytosine5 cytosin methyl
Pubmed's result : temporarily unavailable information

ToxiCat on the selected articles (Beta) :







Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases.
Kelesoglu N , Kim G , Ni J , Pradhan S , Roberts R
EMBO J. 2002 Aug; 21(15): 4183-95
Pmid : 12145218
... to methylation spreading in the genome, suggesting co-operation between de novo and maintenance enzymes during DNA methylation ... The catalytic domain is homologous to prokaryotic (cytosine-5) methyltransferases and contains the catalytic PC dipeptide, while the ...




Mammalian DNA (cytosine-5) methyltransferases and their expression.
Esteve P , Pradhan S
Clin Immunol. 2003 Oct; 109(1): 6-16
Pmid : 14585271
... as the de novo enzyme, whereas the other maintains the methylation status of the daughter strand during DNA ... the methylation status of the daughter strand during DNA replication and thus is referred to as a maintenance ...




Role for DNA methylation in the control of cell type specific maspin expression.
Domann F , Duan H , Futscher B , Hanigan C , Holtan N , Oshiro M , Wozniak R
Nat Genet. 2002 Jun; 31(2): 175-9
Pmid : 12021783
... In addition, cytosine methylation has long been speculated to be involved in the establishment and maintenance of cell ... These findings indicate that cytosine methylation is important in the establishment and maintenance of cell type restricted gene ...




Cytosine methylation and DNA repair.
Walsh C , Xu G
Curr Top Microbiol Immunol. 2006 2006 ; 301: 283-315
Pmid : 16570853
... remethylation of the replacement cytosine, presumably coupling repair to methylation by either the maintenance methylase Dnmt1 or a ... Cytosine methylation is a common form of post-replicative DNA modification seen in both bacteria and eukaryotes ...




[DNA methylation regulating factors in plants].
Liu M , Lu C , Xia H , Xia X , Yin W
Yi Chuan. 2008 Apr; 30(4): 426-32
Pmid : 18424412
... The functions and interactions of DNA methylation regulating factors, the establishment, maintenance and removement mechanisms of DNA methylations ... DNA methylation regulating factors, the establishment, maintenance and removement mechanisms of DNA methylations are reviewed in this paper ...




Perpetuation of cytosine methylation in Ascobolus immersus implies a novel type of maintenance methylase.
Faugeron G , Goyon C , Nogueira T
J Mol Biol. 1994 Jul; 240(1): 42-51
Pmid : 8021939
... Perpetuation of cytosine methylation in Ascobolus immersus implies a novel type of maintenance methylase ... Although the DNA molecules were not all methylated with the same intensity, all cytosine residues in the methylated ...




Analysis of DNA methylation in plants by bisulfite sequencing.
Foerster A , Mittelsten Scheid O
Methods Mol Biol. 2010 2010 ; 631: 1-11
Pmid : 20204863
... modification of genomic DNA in many different eukaryotes, and it is frequently involved in transcriptional regulation of genes ... We describe the application of bisulfite sequencing for the analysis of DNA methylation at defined individual sequences of ...




Restriction enzyme BstZ17I is sensitive to cytosine methylation.
Kanduri C
FEMS Microbiol Lett. 2001 Jun; 200(2): 191-3
Pmid : 11425474
... restriction enzyme is sensitive to cytosine methylation that occurs 3' and/or 5' of the canonical recognition sequence ... In this report, I show that the BstZ17I restriction enzyme is sensitive to cytosine methylation ...




Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.
Sowers L , Valinluck V
Cancer Res. 2007 Feb; 67(3): 946-50
Pmid : 17283125
... methyl group of 5-methylcytosine, with the formation of 5-hydroxymethylcytosine, prevents DNMT1 methylation of the target cytosine ... In contrast, oxidation damage of the methyl group of 5-methylcytosine, with the formation of 5-hydroxymethylcytosine, prevents ...




Eukaryotic cytosine methyltransferases.
Bestor T , Goll M
Annu Rev Biochem. 2005 2005 ; 74: 481-514
Pmid : 15952895
... of gene expression, do not appear to be involved in the establishment or maintenance of genomic methylation patterns ... of histone lysine methylation, small RNAs and components of the RNAi pathway, and divergent and catalytically inert cytosine ...

ToxiCat on the selected articles (Beta) :







Reviving a dead enzyme: cytosine deaminations promoted by an inactive DNA methyltransferase and an S-adenosylmethionine analogue.
Bhagwat A , Sharath A , Weinhold E
Biochemistry. 2000 Nov; 39(47): 14611-6
Pmid : 11087417
... in methyl transfer and cytosine deamination, they cause cytosine deaminations in the presence of AA in the reaction ... of cytosine within specific sequences (C5 Mtases) deaminate the target cytosine to uracil if the methyl donor S ...




Sensitivity of the restriction endonucleases HaeIII, BsrI, EaeI and CfrI to cytosine N4-methylation.
Piekarowicz A , Radlinska M
Acta Microbiol Pol. 1998 1998 ; 47(4): 405-7
Pmid : 10333562
... these enzymes, except NgoII, are inhibited by cytosine N4-methylation of the second 5' cytosine residue within the ... except NgoII, are inhibited by cytosine N4-methylation of the second 5' cytosine residue within the recognition sequence ...




An Arabidopsis SET domain protein required for maintenance but not establishment of DNA methylation.
Bartee L , Bender J , Malagnac F
EMBO J. 2002 Dec; 21(24): 6842-52
Pmid : 12486005
... These results suggest that SUVH4 is involved in maintenance but not establishment of methylation at particular genomic regions ... DNA methylation patterning, a genetic screen for mutations that disrupt methylation-correlated silencing of the endogenous gene PAI2 ...




Effect of cobalamin derivatives on in vitro enzymatic DNA methylation: methylcobalamin can act as a methyl donor.
Dirheimer G , Keith G , Pfohl-Leszkowicz A
Biochemistry. 1991 Aug; 30(32): 8045-51
Pmid : 1868079
... from S-adenosyl-methionine to the 5'-position of cytosine through the action of DNA (cytosine-5)-methyltransferase ... methyl groups from S-adenosyl-methionine to the 5'-position of cytosine through the action of DNA (cytosine ...




Cooperative activity of DNA methyltransferases for maintenance of symmetrical and non-symmetrical cytosine methylation in Arabidopsis thaliana.
Meyer P , Singh A , Zubko E
Plant J. 2008 Dec; 56(5): 814-23
Pmid : 18665914
... To test which DNA methylation pathways regulate RPS methylation, we examined maintenance of RPS methylation in various mutant ... test which DNA methylation pathways regulate RPS methylation, we examined maintenance of RPS methylation in various mutant backgrounds ...




High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers.
Bouhassira E , Dannenberg L , Figueroa M , Glass J , Greally J , Green R , Hatchwell E , Melnick A , Mo Y , Oda M , Olivier E , Richmond T , Selzer R , Suzuki M , Thompson R , Verma A , Zhang X
Nucleic Acids Res. 2009 Jul; 37(12): 3829-39
Pmid : 19386619
... genome-wide assays involve the generation of a subset (or representation) of the genome following restriction enzyme digestion ... The use of enzymes sensitive to cytosine methylation allows high-throughput analysis of this epigenetic regulatory process ...




Murine DNA cytosine C(5)-methyltransferase: in vitro studies of de novo methylation spreading.
Aubol B , Reich N
Biochem Biophys Res Commun. 2003 Oct; 310(1): 209-14
Pmid : 14511672
... The preference of murine DNA (cytosine-5)-methyltransferase (Dnmt1) for single stranded DNA substrates is increased up to ... Murine DNA cytosine C(5)-methyltransferase: in vitro studies of de novo methylation spreading ...




Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks.
Grange T , Kress C , Thomassin H
Proc Natl Acad Sci U S A. 2006 Jul; 103(30): 11112-7
Pmid : 16840560
... Cytosine methylation at CpG dinucleotides contributes to the epigenetic maintenance of gene silencing ... We show that DNA demethylation is an active process, occurring independently of DNA replication, and in a distributive ...




siRNA-mediated chromatin maintenance and its function in Arabidopsis thaliana.
Habu Y , Kanno T
Biochim Biophys Acta. 2011 Aug; 1809(8): 444-51
Pmid : 21605714
... and siRNAs play a major role in directing cytosine methylation through the process of RNA-directed DNA methylation ... in plants carries cytosine methylation in all sequence contexts, and siRNAs play a major role in directing cytosine ...




PAGE separation of hemi-methylated or unmethylated oligonucleotide substrates to distinguish between maintenance and de novo DNA methyltranferase activity.
Butler J , Lee J , Skalnik D
J Biochem Biophys Methods. 2006 Oct; 68(3): 195-9
Pmid : 16901546
... DNA methyltransferase (DNMT) enzymes catalyze the addition of a methyl group to cytosine residues in DNA ... Appropriate cytosine methylation of CpG dinucleotides is required for normal mammalian development and homeostasis, and quantitative methods are ...

ToxiCat on the selected articles (Beta) :







Determining the conservation of DNA methylation in Arabidopsis.
Jacobsen S , Pellegrini M , Widman N
Epigenetics. 2009 Feb; 4(2): 119-24
Pmid : 19384058
... This detailed profile measures the methylation state of most of the cytosines in the Arabidopsis genome, and allows ... for the first time to address questions regarding the conservation of methylation across duplicated regions of the genome ...




Induction and maintenance of nonsymmetrical DNA methylation in Neurospora.
Allis C , Freitag M , Kothe G , Margolin B , Rountree M , Selker E , Tamaru H
Proc Natl Acad Sci U S A. 2002 Dec; 99: 16485-90
Pmid : 12189210
... The action of DIM-2 is controlled by the DIM-5 histone H3 Lys-9 methyltransferase, which in ... and maintenance methylation are manifestations of a single mechanism in Neurospora, catalyzed by the DIM-2 DNA methyltransferase ...




The epigenetic regulator Cfp1.
Skalnik D
Biomol Concepts. 2010 Dec; 1(5-6): 325-34
Pmid : 25962006
... It physically interacts with DNA methyltransferase 1 and facilitates maintenance cytosine methylation ... CXXC finger protein 1 is a regulator of both cytosine and histone methylation ...




A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns.
Bergstrom C , Genereux D , Laird C , Miner B
Proc Natl Acad Sci U S A. 2005 Apr; 102(16): 5802-7
Pmid : 15827124
... leaving the opposing cytosine unmethylated, as revealed by the patterns of methylation on the two complementary strands of ... cytosine unmethylated, as revealed by the patterns of methylation on the two complementary strands of individual DNA molecules ...




Cytosine methylation of repeated sequences in eukaryotes: the role of DNA pairing.
Bender J
Trends Biochem Sci. 1998 Jul; 23(7): 252-6
Pmid : 9697415
... Cytosine methylation of repeated sequences in eukaryotes: the role of DNA pairing ... Recent data have outlined the substrate requirements for the establishment and maintenance of methylation in eukaryotic repeated sequences ...




Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.
Jaenisch R , Kashevsky H , Lyko F , Mastrangelo M , Orr-Weaver T , Ramsahoye B , Tudor M
Nat Genet. 1999 Nov; 23(3): 363-6
Pmid : 10545955
... Genomic DNA methylation impaired the viability of transgenic flies, suggesting that cytosine methylation has functional consequences for Drosophila ... DNA methylation impaired the viability of transgenic flies, suggesting that cytosine methylation has functional consequences for Drosophila development ...




Maintenance of genomic methylation requires a SWI2/SNF2-like protein.
Jeddeloh J , Richards E , Stokes T
Nat Genet. 1999 May; 22(1): 94-7
Pmid : 10319870
... sequence methylation suggests that ddm1 mutations compromise the efficiency of methylation of newly incorporated cytosines after DNA replication ... DDM1, decrease in DNA methylation) from the flowering plant Arabidopsis thaliana required to maintain normal cytosine methylation patterns ...




DNA methylation systems and targets in plants.
Meyer P
FEBS Lett. 2011 Jul; 585(13): 2008-15
Pmid : 20727353
... Our detailed knowledge about the composition of DNA methylation patterns is contrasted by a poorer understanding of the ... Plants contain three distinct DNA methyltransferase types that are responsible for the establishment and maintenance of cytosine methylation ...




A histone methylation-dependent DNA methylation pathway is uniquely impaired by deficiency in Arabidopsis S-adenosylhomocysteine hydrolase.
Bender J , Ebbs M , Mull L
Genetics. 2006 Nov; 174(3): 1161-71
Pmid : 16951055
... the maintenance of methylation homeostasis in eukaryotes because it is needed to metabolize the by-product of transmethylation ... S-adenosylhomocysteine hydrolase (SAH) is a key enzyme in the maintenance of methylation homeostasis in eukaryotes because it ...




DNA methylation in higher plants: past, present and future.
Ashapkin V , Vanyushin B
Biochim Biophys Acta. 2011 Aug; 1809(8): 360-8
Pmid : 21549230
... it is involved in the control of all genetic functions including transcription, replication, DNA repair, gene transposition and ... The nDNA methylation is carried out by cytosine DNA methyltransferases of, at least, three families ...

ToxiCat on the selected articles (Beta) :







Maintenance DNA methylation of nucleosome core particles.
Okuwaki M , Verreault A
J Biol Chem. 2004 Jan; 279(4): 2904-12
Pmid : 14578347
... The enzyme responsible for maintenance methylation of CpG dinucleotides in vertebrates is DNMT1 ... The presence of DNMT1 in DNA replication foci raises the issue of whether this enzyme needs to gain ...




DNA methyltransferases.
Bestor T , Verdine G
Curr Opin Cell Biol. 1994 Jun; 6(3): 380-9
Pmid : 7917329
... the enzyme to the replication machinery and may be involved in sensing the pre-existing methylation state of ... to the replication machinery and may be involved in sensing the pre-existing methylation state of the DNA ...




Maintenance of genomic methylation patterns during preimplantation development requires the somatic form of DNA methyltransferase 1.
Amamo T , Asano T , Kawamura Y , Kobayashi H , Kurihara H , Kurihara Y , Uchijima Y
Dev Biol. 2008 Jan; 313(1): 335-46
Pmid : 18048024
... DNA methylation during preimplantation development have been identified except for the oocyte form of DNA (cytosine-5)-methyltransferase ... These results indicate that Dnmt1s is responsible for the maintenance methylation of particular genomic regions whose methylation patterns ...




Allosteric activator domain of maintenance human DNA (cytosine-5) methyltransferase and its role in methylation spreading.
Estčve P , Pradhan S
Biochemistry. 2003 May; 42(18): 5321-32
Pmid : 12731873
... Allosteric activator domain of maintenance human DNA (cytosine-5) methyltransferase and its role in methylation spreading ... DNA methylation, bound to the allosteric site of hDNMT1 and inhibited methylation, suggesting Rb may regulate methylation spreading ...




Cytosine methylated DNA synthesized by Taq polymerase used to assay methylation sensitivity of restriction endonuclease HinfI.
Colasanti J , Sundaresan V
Nucleic Acids Res. 1991 Jan; 19(2): 391-4
Pmid : 2014176
... PCR procedure to synthesize DNA of known sequence in which every cytosine is methylated at the 5 position ... simple PCR procedure to synthesize DNA of known sequence in which every cytosine is methylated at the 5 ...




Characterization of DNA methyltransferase from bovine thymus cells.
Noguchi H , Sager R , Sano H
Eur J Biochem. 1983 Sep; 135(2): 181-5
Pmid : 6884360
... Sequence specificity analysis revealed that about 60% of the total methylation occurred in the 5'd(C-G ... analysis revealed that about 60% of the total methylation occurred in the 5'd(C-G)3' doublet ...




Identification of a region of the DNMT1 methyltransferase that regulates the maintenance of genomic imprints.
Borowczyk E , Chaillet J , Cirio M , D'Aiuto L , Mohan K
Proc Natl Acad Sci U S A. 2009 Dec; 106(49): 20806-11
Pmid : 19923434
... Reprogramming of DNA methylation patterns during mammalian preimplantation development involves the concurrent maintenance of methylation on differentially methylated ... Because the DNMT1 cytosine methyltransferase governs maintenance methylation in mammals, rearrangements of non-DMD, but not DMD methylation ...




[Methylation and expression of the FMR1 gene].
Morón F , Pintado E
Rev Neurol. 2001 Oct; 33: S57-62
Pmid : 12447821
... DNA methylation, the enzymes and proteins involved in the repression complex and the importance of methylation of FMR1 ... The comprehension of the mechanisms by which methylation induces the silencing of the genes and the study of ...




Changes of cytosine methylation induced by wide hybridization and allopolyploidy in Cucumis.
Chen J , Chen L
Genome. 2008 Oct; 51(10): 789-99
Pmid : 18923530
... Observations in different generations of the allotetraploid found that the extent of change in cytosine methylation pattern between ... revealed a twofold difference in the level of cytosine methylation between the reciprocal F1 hybrids and the allotetraploid ...




DNA methylation profiling in zebrafish.
Cairns B , Hammoud S , Jones D , Nix D , Potok M , Wu S , Zhang H
Methods Cell Biol. 2011 2011 ; 104: 327-39
Pmid : 21924171
... Virtually all of the enzymes and factors involved in the deposition, binding, and removal of cytosine methylation are ... excellent model for understanding the use of DNA methylation in the control of gene regulation and other processes ...

ToxiCat on the selected articles (Beta) :







Arabidopsis DEMETER-LIKE proteins DML2 and DML3 are required for appropriate distribution of DNA methylation marks.
Ariza R , Morales-Ruiz T , Ortega-Galisteo A , Roldán-Arjona T
Plant Mol Biol. 2008 Aug; 67(6): 671-81
Pmid : 18493721
... Cytosine DNA methylation is a stable epigenetic mark for maintenance of gene silencing across cellular divisions, but it ... not only for removing DNA methylation marks from improperly-methylated cytosines, but also for maintenance of high methylation ...




On the substrate specificity of DNA methyltransferases. adenine-N6 DNA methyltransferases also modify cytosine residues at position N4.
Christ F , Fatemi M , Jeltsch A , Roth M
J Biol Chem. 1999 Jul; 274(28): 19538-44
Pmid : 10391886
... Methylation of DNA is important in many organisms and essential in mammals ... In contrast, methylation of adenine residues by the cytosine-N4 methyltransferase M ...




DNA methylation. Inhibition of de novo and maintenance methylation in vitro by RNA and synthetic polynucleotides.
Bolden A , Siedlecki J , Ward C , Weissbach A
J Biol Chem. 1984 Oct; 259(20): 12437-43
Pmid : 6208188
... the guanine residue itself in the binding of the DNA methylase to dCpdG, the site of cytosine methylation ... to DNA in the nucleosome structure and the DNA replication complex may determine specific sites of DNA methylation ...




Mechanism of CpG DNA methyltransferases M.SssI and Dnmt3a studied by DNA containing 2-aminopurine.
Cherepanova N , Gromova E , Minero A , Rakhimova A
Nucleosides Nucleotides Nucleic Acids. 2011 Jul; 30(7-8): 619-31
Pmid : 21888552
... located adjacent to the target cytosine in the CpG site dramatically reduces the stability of the methyltransferase-DNA ... Removal of the 6-oxo group of the guanine located adjacent to the target cytosine in the CpG ...




Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
Bettuzzi S , Patra S
Biochemistry (Mosc). 2009 Jun; 74(6): 613-9
Pmid : 19645665
... the mechanism of DNA (cytosine-5-carbon) methylation ((Me)CpG-DNA or (Me)CpNpG-DNA formation) and (Me ... DNA (cytosine-5-carbon) methylation is one of the hallmarks of mammalian chromatin modifications ...




Purification and characterization of rice DNA methyltransferase.
Chauvatcharin N , Krittanai P , Narangajavana J , Teerawanichpan P
Plant Physiol Biochem. 2009 Aug; 47(8): 671-80
Pmid : 19401269
... and the results suggested that the cytosine methylation level is not directly correlated with the DNA MTase activity ... The purified protein preferred hemi-methylated DNA substrate, suggesting the maintenance activity of methylation ...




Detection of cytosine methylation and mapping of a gene influencing cytosine methylation in the genome of Citrus.
Cai Q , Guy C , Moore G
Genome. 1996 Apr; 39(2): 235-42
Pmid : 8984000
... Detection of cytosine methylation and mapping of a gene influencing cytosine methylation in the genome of Citrus ... was developed to detect DNA methylation in the Citrus genome using random amplification coupled with restriction enzyme digestion ...




Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences.
Flynn J , Glickman J , Reich N
Biochemistry. 1996 Jun; 35(23): 7308-15
Pmid : 8652507
... certainly capable of both maintenance and de novo methylation and that maintenance of the genomic methylation pattern is ... and that maintenance of the genomic methylation pattern is preferred over the de novo establishment of new patterns ...




Evidence for cytosine methylation of non-symmetrical sequences in transgenic Petunia hybrida.
Meyer P , Niedenhof I , ten Lohuis M
EMBO J. 1994 May; 13(9): 2084-8
Pmid : 8187761
... as CpG and CpNpG, which provide the signal for faithful transmission of symmetrical methylation patterns by maintenance methylase ... have analysed cytosine methylation patterns within a hypermethylated and a hypomethylated state of a transgene in Petunia hybrida ...




Substrate specificity of new methyl-directed DNA endonuclease GlaI.
Degtyarev S , Nayakshina T , Tarasova G
BMC Mol Biol. 2008 2008 ; 9: 7-7
Pmid : 18194583
... of GlaI activity on the quantity and location of 5-methylcytosines in the enzyme recognition sequence 5'-GCGC ... in detail the composition of recognition sequence and effect of the methylated cytosines on the efficiency of DNA ...