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Query : Which is the most widely used model for the study of multiple sclerosis (MS)? , reformulated as wide model multipl sclerosi ms
Pubmed's result : temporarily unavailable information

ToxiCat on the selected articles (Beta) :







Genes associated with multiple sclerosis: 15 and counting.
Borovecki F , Brinar V , Habek M
Expert Rev Mol Diagn. 2010 Oct; 10(7): 857-61
Pmid : 20964605
... In all of these genes, in a study by the International Multiple Sclerosis Genetics Consortium, the classic MS ... the International Multiple Sclerosis Genetics Consortium, the classic MS risk locus, HLA-DRB1, stood out with remarkably strong ...




Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.
Aulchenko Y , Broer L , Ebers G , Hintzen R , Hoppenbrouwers I , Janssens A , Kayser M , Oostra B , Ramagopalan S , van Duijn C
J Hum Genet. 2009 Nov; 54(11): 676-80
Pmid : 19834503
... our study, the original IMSGC results and the results of a recent replication study performed in the Australian ... study, the original IMSGC results and the results of a recent replication study performed in the Australian population ...




Urological and sexual problems in multiple sclerosis.
Blaivas J , Chancellor M
Clin Neurosci. 1994 1994 ; 2(3-4): 189-95
Pmid : 7749887
... For many MS patients, urinary symptoms may be the most socially disabling features of the illness ... Urologic dysfunction is a common and devastating feature of multiple sclerosis (MS ...




[Orbitofrontal dysfunction in multiple sclerosis: Iowa Gambling Task].
García-Molina A , Junqué i Plaja C , Rodríguez Rajo P , Roig-Rovira T , Vendrell Gómez P
Psicothema. 2008 Aug; 20(3): 445-9
Pmid : 18674441
... The current study examined the decision-making processes of patients with multiple sclerosis (MS) using a computerized version ... making processes of patients with multiple sclerosis (MS) using a computerized version of the Iowa Gambling Task (IGT ...




[Diagnostic criteria of multiple sclerosis: electrophysiological criteria].
André-Obadia N , Fischer C , Mauguière F
Rev Neurol (Paris). 2001 Sep; 157(8-9): 974-80
Pmid : 11787363
... multiple sclerosis has been changed since MRI is now widely and easily used for the diagnosis of MS ... evoked potentials in multiple sclerosis (MS) for the past 30 years, in the diagnosis of MS, to disclose ...




What is Next for the Genetics of Multiple Sclerosis?
Dyment D , Ramagopalan S
Autoimmune Dis. 2011 2011 ; 2011: 519450-519450
Pmid : 21541245
... The strongest genetic risk factor for MS is the major histocompatibility complex which was identified in the 1 ... approximately 20 new genes for MS, we ask the question-what is next for the genetics of MS ...




Long term azathioprine fails to prevent onset of multiple sclerosis: report of two cases.
Blumhardt L , Constantinescu C , Whiteley A
Mult Scler. 2000 Oct; 6(5): 362-3
Pmid : 11064448
... Azathioprine is an immunosuppressive drug widely used in the treatment of chronic inflammatory diseases, including Multiple Sclerosis (MS ... We report two patients who developed the first manifestations of clinically definite multiple sclerosis while on long term ...




Multiple sclerosis and associated diseases: a relationship to diabetes mellitus.
Warren K , Warren S
Can J Neurol Sci. 1981 Feb; 8(1): 35-9
Pmid : 7225955
... One hundred multiple sclerosis (MS) patients and hospital controls were compared for coexisting illnesses, and other illnesses among ... report a family history of diabetes mellitus than MS patients who had no other relative with multiple sclerosis ...




Symptomatic therapies of multiple sclerosis.
McGowan D , Metz L , Patten S
Biomed Pharmacother. 1999 Sep; 53(8): 371-9
Pmid : 10554671
... Symptom management is the assessment and treatment of the manifestations of multiple sclerosis (MS ... This article will review the medical and surgical options used in the management of primary MS symptoms ...




Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.
Bettecken T , Cepok S , Hemmer B , Holsboer F , Ising M , Knop M , Kroner A , Müller-Myhsok B , Müller-Sarnowski F , Nischwitz S , Pfister H , Rieckmann P , Roeske D , Uhr M , Weber F , Wolf C
J Neuroimmunol. 2010 Oct; 227(1-2): 162-6
Pmid : 20598377
... were able to replicate the association of the HLA region with MS independently of previous case control studies ... association of MS with variants in two new genes, the VAV2 gene and the gene for ZNF433 ...

ToxiCat on the selected articles (Beta) :







[Clinical surveillance of patients with multiple sclerosis].
Cazzato G , Zorzon M
Recenti Prog Med. 2003 Apr; 94(4): 173-6
Pmid : 12677789
... exacerbations, on the evaluation of disease progression and on the management of the wide range of MS symptoms ... and treatment of disease exacerbations, on the evaluation of disease progression and on the management of the wide ...




Is multiple sclerosis severity a genetically influenced trait?
Cocco E , Marrosu M
Neurol Sci. 2000 2000 ; 21(4): S843-7
Pmid : 11205360
... The pathological entity MS has a wide phenotype, and also the severity of the disease is widely variable ... about the modifying role of different genes in the course and the severity of MS are here discussed ...




[Cytotoxic antibodies in multiple sclerosis].
Collard M , Marescaux C , Mayer S , Rumbach L , Tongio M , Warter J
Pathol Biol (Paris). 1987 Mar; 35(3): 307-12
Pmid : 3295696
... lymphocytes and monocytes were detected in 12 of 21 multiple sclerosis (MS) patients at 15 degrees C using ... were detected in 12 of 21 multiple sclerosis (MS) patients at 15 degrees C using a microcytotoxicity technique ...




[New gene map for multiple sclerosis].
Celius E , Harbo H , Lie B , Lorentzen A , Spurkland A
Tidsskr Nor Laegeforen. 2011 Nov; 131(21): 2126-30
Pmid : 22048209
... The etiology of the disease is unknown, but both environmental and genetic factors contribute to the risk of ... Multiple sclerosis (MS) is a demyelinating, inflammatory disease of the central nervous system which affects young adults with ...




Dietary patterns in clinical subtypes of multiple sclerosis: an exploratory study.
De Keyser J , Mellema S , Ramsaransing G
Nutr J. 2009 2009 ; 8: 36-36
Pmid : 19664270
... The intake measured was also compared to the intake of the Dutch population and to the recommended daily ... whether variations in dietary intake may be related to the severity of the disease course in multiple sclerosis ...




Multiple sclerosis as a retroviral disease? Epidemiological considerations in relation to HTLV-I epidemiology.
Haahr S , Møller-Larsen A , Sommerlund M
Neuroepidemiology. 1991 1991 ; 10(5-6): 232-5
Pmid : 1665894
... The intrafamilial epidemiology of multiple sclerosis was compared with the known intrafamilial epidemiology of infections with HTLV-I ... Through the Danish Multiple Sclerosis Registry, information was obtained on 79 parent-child cases of multiple sclerosis, and ...




Fatigue in multiple sclerosis.
Alvarez L , Krupp L , LaRocca N , Scheinberg L
Arch Neurol. 1988 Apr; 45(4): 435-7
Pmid : 3355400
... Fatigue is a frequent symptom in multiple sclerosis (MS) that can interfere with a patient's daily functioning ... The cause of MS fatigue, its clinical characteristics, and its relationship to other symptoms remain poorly understood ...




Successful treatment of co-morbid schizophrenia and multiple sclerosis.
Behere R , Gangadhar B , Rao N , Sharma E , Varambally S , Venkatasubramanian G
Asian J Psychiatr. 2010 Dec; 3(4): 235-6
Pmid : 23050895
... We, for the first time, report a patient with MS and paranoid schizophrenia successfully treated with concurrent use ... Successful treatment of co-morbid schizophrenia and multiple sclerosis ...




[Multiple sclerosis at the time of world-wide use of disease modifying treatment].
Boiko A , Gusev E
Zh Nevrol Psikhiatr Im S S Korsakova. 2009 2009 ; 109(7): 4-9
Pmid : 19894306
... The review discusses issues of multiple sclerosis (MS) management at the time of world-wide use of effective ... at the time of world-wide use of effective treatment - disease modifying treatment including the influence of the ...




Alteration of lipid-phase behavior in multiple sclerosis myelin revealed by wide-angle x-ray diffraction.
Chia L , Moscarello M , Thompson J
Proc Natl Acad Sci U S A. 1984 Mar; 81(6): 1871-4
Pmid : 6584921
... observed, the inability of MS myelin protein to organize the lipid reflects a qualitative difference in the proteins ... The transition temperature for liposomes of MS myelin lipid was essentially similar to that for isolated MS myelin ...

ToxiCat on the selected articles (Beta) :







Walking and fatigue in multiple sclerosis: the role of the corticospinal system.
Dengler R , Rollnik J , Schubert M , Wohlfarth K
Muscle Nerve. 1998 Aug; 21(8): 1068-70
Pmid : 9655126
... Walking and fatigue in multiple sclerosis: the role of the corticospinal system ... evoked potentials (MEPs) of leg muscles in controls and patients with multiple sclerosis (MS) before and after walking ...




Risk factors in the development of multiple sclerosis.
Ascherio A , Munger K
Expert Rev Clin Immunol. 2007 Sep; 3(5): 739-48
Pmid : 20477024
... Multiple sclerosis (MS) is a T-cell-mediated demyelinating disease of the CNS with no known cure or ... sclerosis (MS) is a T-cell-mediated demyelinating disease of the CNS with no known cure or cause ...




Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis.
Alcina A , Arnal C , Catalá-Rabasa A , Delgado C , Ebers G , Fedetz M , Fernández O , Izquierdo G , Leyva L , Lucas M , Matesanz F , Ndagire D , Ramagopalan S
Eur J Hum Genet. 2010 May; 18(5): 618-20
Pmid : 19935835
... This marker is located on chromosome 1p36.22, which is 1 Mb away from the MS-associated ... A recent genome-wide association study (GWAS) performed by the The Wellcome Trust Case-Control Consortium based on ...




A genome-wide screen for association in Hungarian multiple sclerosis.
Bencsik K , Benediktsson K , Compston A , Foltynie T , Fossdal R , Jonasdottir A , Rajda C , Sawcer S , Seres E , Setakis E , Vécsei L
J Neuroimmunol. 2003 Oct; 143(1-2): 84-7
Pmid : 14575920
... Although the pathogenesis of multiple sclerosis (MS) is not fully understood, substantial evidence points to the involvement of ... pathogenesis of multiple sclerosis (MS) is not fully understood, substantial evidence points to the involvement of genetic factors ...




Anticipation of age at onset in familial multiple sclerosis.
Arbizu T , Bau L , Gubieras L , Kremenchutzky M , Martínez-Yélamos S , Matas E , Romero-Pinel L
Eur J Neurol. 2010 Apr; 17(4): 572-5
Pmid : 20002735
... There is an anticipation of the age at onset of MS in the younger generations of patients with ... an anticipation of the age at onset of MS in the younger generations of patients with familial MS ...




Two genome-wide linkage disequilibrium screens in Scandinavian multiple sclerosis patients.
Akesson E , Andersen O , Celius E , Compston A , Datta P , Harbo H , Hillert J , Modin H , Myhr K , Oturai A , Ryder L , Sandberg-Wollheim M , Sawcer S , Setakis E , Sorensen P , Spurkland A , Svejgaard A , Vartdal F
J Neuroimmunol. 2003 Oct; 143(1-2): 101-6
Pmid : 14575924
... We report the first two genome-wide screens for linkage disequilibrium between putative multiple sclerosis (MS) susceptibility genes ... linkage disequilibrium between putative multiple sclerosis (MS) susceptibility genes and genetic markers performed in the genetically homogenous Scandinavian ...




In vitro IgG synthesis by peripheral blood lymphocytes of multiple sclerosis patients and normal individuals. Effect of multiple sclerosis and non-multiple sclerosis brain antigens.
Birkeboek N , Rastogi S
Eur Neurol. 1983 1983 ; 22(2): 131-7
Pmid : 6840145
... IgG synthesis by lymphocytes of multiple sclerosis (MS) patients and normal individuals in the presence of MS and ... and normal individuals in the presence of MS and non-MS brain antigens and in the absence of ...




Chromosome 17q22-q24 and multiple sclerosis genetic susceptibility. American-French Multiple Sclerosis Genetic Group.
Arnaud I , Babron M , Clanet M , Clerget-Darpoux F , Cournu I , Eichenbaum-Voline S , Fontaine B , Haines J , Hauser S , Liblau R , Lyon-Caen O , Oksenberg J , Pericak-Vance M , Semama G
Genes Immun. 1999 Nov; 1(2): 149-50
Pmid : 11196661
... Recently, genome-wide searches for multiple sclerosis (MS) susceptibility genes have suggested that the chromosome 17q22-q24 ... region might contain a gene increasing the sibling recurrence risk of MS over 1.4, rendering the existence ...




A further study on the prevalence of multiple sclerosis in Sicily: Caltanissetta city.
Dean G , Elian M , Giordano D , Grimaldi G , Savettieri G , Ventura A
Acta Neurol Scand. 1986 Jan; 73(1): 71-5
Pmid : 3953260
... The high prevalence of multiple sclerosis in Caltanissetta confirms the previous data on Sicily and emphasises the importance ... the previous data on Sicily and emphasises the importance of small population studies in the epidemiology of MS ...




Epidemiology and genetics of multiple sclerosis.
Compston A , Sadovnick A
Curr Opin Neurol Neurosurg. 1992 Apr; 5(2): 175-81
Pmid : 1623245
... Epidemiological data suggest an aetiological role for both genetic and environmental factors in multiple sclerosis (MS), but these ... for both genetic and environmental factors in multiple sclerosis (MS), but these have yet to be fully characterized ...

ToxiCat on the selected articles (Beta) :







The diagnosis of multiple sclerosis and the clinical subtypes.
Hurwitz B
Ann Indian Acad Neurol. 2009 Oct; 12(4): 226-30
Pmid : 20182569
... The diagnosis of multiple sclerosis (MS) requires objective findings referable to the central nervous system ... The diagnosis of multiple sclerosis and the clinical subtypes ...




Pathway and network-based analysis of genome-wide association studies in multiple sclerosis.
Baranzini S , Barnes M , Galwey N , Gibson R , Hauser S , Kappos L , Khankhanian P , Lindberg R , Matthews P , Oksenberg J , Pelletier D , Polman C , Uitdehaag B , Wang J , Wu W
Hum Mol Genet. 2009 Jun; 18(11): 2078-90
Pmid : 19286671
... Typically, the number of markers in which the evidence for association exceeds the genome-wide significance threshold is ... In addition to the immunological pathways previously identified, we report here for the first time the potential involvement ...




Depression in multiple sclerosis: critique of the research literature.
Acorn S , Andersen S
J Neurosci Nurs. 1990 Aug; 22(4): 209-14
Pmid : 2144554
... The purpose of this article is to provide a review of the research literature on depression in multiple ... purpose of this article is to provide a review of the research literature on depression in multiple sclerosis ...




Anti-nuclear antibodies and the optic-spinal form of multiple sclerosis.
Fukazawa T , Hamada K , Hamada T , Kikuchi S , Miyasaka K , Sasaki H , Tashiro K
J Neurol. 1997 Aug; 244(8): 483-8
Pmid : 9309553
... a diagnosis of the optic-spinal form of multiple sclerosis (OpS-MS) and 13 of 59 patients with ... higher) in sera from 11 of 16 patients with a diagnosis of the optic-spinal form of multiple ...




Multiple sclerosis and infectious childhood diseases.
Bachmann S , Kesselring J
Neuroepidemiology. 1998 1998 ; 17(3): 154-60
Pmid : 9648121
... The mean age of the MS patients was 50.7 years and the mean age at onset of ... These results are compatible with the hypothesis that the risk of developing multiple sclerosis may be associated with ...




Do nurses or doctors have an increased risk of developing multiple sclerosis?
Dean G , Gray R
J Neurol Neurosurg Psychiatry. 1990 Oct; 53(10): 899-902
Pmid : 2133986
... Possible explanations for the cluster of multiple sclerosis among nurses in Key West are discussed ... Allowance for the inter-class variability in MS death rates did not materially affect the conclusion that death ...




Peripheral neuropathy in multiple sclerosis.
Drake M
J Natl Med Assoc. 1987 Jun; 79(6): 672-3
Pmid : 3039153
... Evidence suggests that the spectrum of multiple sclerosis (MS) may extend to peripheral nerve dysfunction ... The author describes a patient with MS whose peripheral nervous system was involved ...




Movement disorders in multiple sclerosis.
Gancher S , Herndon R , Mao C
Mov Disord. 1988 1988 ; 3(2): 109-16
Pmid : 3065639
... cases of parkinsonism and a case of chorea associated with MS are reported, and the literature is reviewed ... Two cases of parkinsonism and a case of chorea associated with MS are reported, and the literature is ...




Pathological laughing and crying in multiple sclerosis: a preliminary report suggesting a role for the prefrontal cortex.
Feinstein A , Feinstein K , Gray T , O'Connor P
Mult Scler. 1999 Apr; 5(2): 69-73
Pmid : 10335513
... The relevance of these findings to the pathogenesis of PLC is discussed, in particular whether the syndrome is ... PLC is discussed, in particular whether the syndrome is, in part, mediated by dysfunction of the prefrontal cortex ...




Multiple sclerosis in the Shetland Islands: an update.
Cook S , Dowling P , MacDonald J , Poskanzer D , Tapp W
Acta Neurol Scand. 1988 Feb; 77(2): 148-51
Pmid : 3259061
... of MS, or mean age of the MS population in Shetland has been found since the last survey ... Annual incidence rates of multiple sclerosis (MS) in the Shetland Islands have been updated from 1938 to ...

ToxiCat on the selected articles (Beta) :







Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655.
Börnsen L , Celius E , Christensen J , Harbo H , Hillert J , Kockum I , Lindén M , Mero I , Myhr K , Olsson T , Oturai A , Sellebjerg F , Søndergaard H , Sørensen P
Eur J Hum Genet. 2011 Oct; 19(10): 1100-3
Pmid : 21610746
... Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763 ... in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655 ...




Multiple sclerosis genetics 2010.
McElroy J , Oksenberg J
Neurol Clin. 2011 May; 29(2): 219-31
Pmid : 21439438
... wide, with the primary signal arising from the HLA-DRB1gene in the class II segment of the locus ... susceptibility locus genome-wide, with the primary signal arising from the HLA-DRB1gene in the class II segment ...




A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.
Aarseth J , Ban M , Celius E , Dudbridge F , Elovaara I , Harbo H , Hillert J , Kemppinen A , Kockum I , Lie B , Link J , Lorentzen A , Masterman T , Mero I , Myhr K , Olsson T , Oturai A , Saarela J , Sellebjerg F , Smestad C , Spurkland A , Søndergaard H
Eur J Hum Genet. 2010 Apr; 18(4): 502-4
Pmid : 19888296
... A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis ... However, because of the low frequency of the minor allele (minor allele frequency=0.04), genome-wide significant ...




Recent developments in the assessment of quality of life in multiple sclerosis (MS).
Andrews H , Fischer J , LaRocca N , Miller D , Paty D , Ritvo P
Mult Scler. 1999 Aug; 5(4): 251-9
Pmid : 10467384
... health-related quality of life (HRQL), and describes the development of the Multiple Sclerosis Quality of Life Inventory ... related quality of life (HRQL), and describes the development of the Multiple Sclerosis Quality of Life Inventory (MSQLI ...




[Diagnosis and differential diagnosis in multiple sclerosis].
Huber S , Kappos L
Praxis (Bern 1994). 1997 Jan; 86(3): 46-54
Pmid : 9045284
... The diagnosis of multiple sclerosis (MS) relies on the occurrence of characteristic symptoms, on the patient's history ... occurrence of characteristic symptoms, on the patient's history and on the correct interpretation of nowadays very sensitive ...




Current status of computerization of multiple sclerosis clinical data for research in Europe and North America: the EDMUS/MS-COSTAR connection. European Database for Multiple Sclerosis. Multiple Sclerosis-Computed Stored Ambulatory Record.
Confavreux C , Paty D
Neurology. 1995 Mar; 45(3): 573-6
Pmid : 7898721
... Current status of computerization of multiple sclerosis clinical data for research in Europe and North America: the EDMUS ... computerization of multiple sclerosis clinical data for research in Europe and North America: the EDMUS/MS-COSTAR connection ...




Schizophrenia and multiple sclerosis. Distribution in Italy.
Cappelletty G , Kauffman I , Templer D
Br J Psychiatry. 1988 Sep; 153: 389-90
Pmid : 3250677
... earlier report of USA states with high levels of schizophrenia also having high levels of multiple sclerosis (MS ... The present study extended an earlier report of USA states with high levels of schizophrenia also having high ...




Insight from genome-wide association studies in rheumatoid arthritis and multiple sclerosis.
Kochi Y , Okada Y , Suzuki A , Yamamoto K
FEBS Lett. 2011 Dec; 585(23): 3627-32
Pmid : 21600898
... This review focuses on the search for genetic variants that influence the susceptibility to RA and MS as ... that influence the susceptibility to RA and MS as typical autoimmune diseases and discusses the future of GWAS ...




[Multiple sclerosis and pregnancy].
Chofflon M , Lalive P
Rev Med Suisse. 2009 Apr; 5(201): 938-40
Pmid : 19476055
... Mulltiple sclerosis and pregnancy Multiple sclerosis (MS) is diagnosed between the second and fourth decade ... In other words could the pregnancy worsen MS and could MS represent specific risks for the pregnancy ...




[Diagnostic criteria of borderline forms of multiple sclerosis].
Dupel-Pottier C
Rev Neurol (Paris). 2001 Sep; 157(8-9): 935-43
Pmid : 11787358
... Border forms of multiple sclerosis (MS) can be separated in two groups: either they are variants of MS ... s concentric sclerosis, Schilder's myelinoclastic diffuse sclerosis and MS simulating a mass lesion, and for the second ...