Short Bio
Linea Schmidt is currently pursuing a PhD in the Department of Digital Health, Economics and Policy at the Hasso Plattner Institute. Her research interests include novel care models, such as remote patient monitoring and disease management programs, as well as digital health entrepreneurship. She has previously studied digital health and holds an undergraduate degree in Business Administration, with a focus on business informatics, at Freie Universität Berlin. Linea completed her Master's Thesis in collaboration with the Hasso Plattner Institute for Digital Health at Mount Sinai New York, where she conducted a research stay and worked on natural language processing methods for electronic health records. In addition to her academic pursuits and work at different university chairs, she has gained work experience in remote patient monitoring for chronic heart failure and supported multiple research projects at the University Hospital in Düsseldorf, mainly focusing on remote patient monitoring for neurological diseases. Furthermore, Linea is a board member of the German Society for Digital Medicine.
Research Interests
My research is dedicated to advancing innovative care models and fostering entrepreneurship within the digital health landscape. I primarily explore the development and implementation of Digital Therapeutics (DTx) and Digital Health Applications (such as DiGA in Germany), as well as Disease Management Programs (DMP) and Remote Patient Monitoring (RPM) systems.
Part of my work leverages data from the Mount Sinai Health System in New York, in collaboration with the Hasso Plattner Institute (HPI) for Digital Health at Mount Sinai.
In addition, I collaborate with the HPI Engine to cultivate a thriving ecosystem that supports digital health entrepreneurs.
Teaching
Summer Term 2026
Building Products for Digital Health
Winter Term 2025/2026
Digital Health Spark - Igniting Need-Driven Innovation in Healthcare
TRACED Master Project
Summer Term 2025
Building Products for Digital Health
Guest Lecture: 21st Century Health Care Businesses: Regulatory, Legal, and Public Policy Aspects
Winter Term 2024/2025:
Digital Health Spark - Igniting Need-Driven Innovation in Healthcare
AUDiCT Master Project
Summer Term 2024:
Seminar Current Developments in Electronic Health Records
Product Builder Digital Health
Guest Lecture: 21st Century Health Care Businesses: Regulatory, Legal, and Public Policy Aspects
Winter Term 2023/2024
Digital Health Spark - Igniting Need-Driven Innovation in Healthcare
Short Resume
Fall 2025: Research stay at MIT Sloan School of Management in Boston
Since 2023: PhD Candidate in Digital Health at HPI
2020 - 2023: Digital Health (M.Sc.) at HPI
2022/2023: Research stay at Hasso Plattner Institute for Digital Health at Mount Sinai (New York)
2017 - 2020: Business Administration with a focus in Business Informatics (B.Sc.) at Freie Universität Berlin
Publications
- Schmidt, L., Langenberger, B., Schirmann, F., Reif, S., & Stern, A. D. (2026). Mechanisms of action for digital therapeutics. Npj Digital Medicine. https://doi.org/10.1038/s41746-026-02502-y
- Brecher, A.-L., Kraft, L., Schmidt, L., Platzbecker, A. S., Stern, A. D., & Amelung, V. E. (2026). Built to Run, but Stuck in First Gear? Lessons Learned and the Road Ahead for Digital Health Applications 2.0. HMPI: Health Management, Policy & Innovation, (February 2026, Volume 11, Issue 1). https://hmpi.org/2026/02/18/built-to-run-but-stuck-in-first-gear-lessons-learned-and-the-road-ahead-for-digital-health-applications-2-0/
- Schmidt, L., Ibing, S., Borchert, F., Hugo, J., Marshall, A. A., Peraza, J., Cho, J. H., Böttinger, E. P., Renard, B. Y., & Ungaro, R. C. (2026). Automating clinical phenotyping using natural language processing. Communications Medicine, 6(1), 77. https://doi.org/10.1038/s43856-025-01337-0
- Epping, P. Z., Hagler, R., Werner, N. M., Voth, J., Schmidt, L., Huntemann, N., Stern, A. D., Ruck, T., Meuth, S. G., Pawlitzki, M., & Masanneck, L. (2026). Case-Based Lessons on Remote Patient Monitoring in Neurology Using Consumer-Grade Wearables. Journal of Central Nervous System Disease, 18, 11795735261419641. https://doi.org/10.1177/11795735261419641
- Schmidt, L., Mastroanastasiou, A., & Stern, A. D. (2025). Remote Patient Monitoring – Ein Blick über den Atlantik und was wir aus den USA lernen können. https://www.wirtschaftsdienst.eu/inhalt/jahr/2025/heft/7/beitrag/remote-patient-monitoring-ein-blick-ueber-den-atlantik-und-was-wir-aus-den-usa-lernen-koennen.html
- Masanneck, L., Voth, J., Gmahl, N., Jendretzky, K., Huntemann, N., Werner, N. M., Schmidt, L., Oeztuerk, M., Quint, P., Schroeter, C. B., Hartung, H. P., Skripuletz, T., Meyer zu Hörste, G., Ruck, T., Meuth, S. G., & Pawlitzki, M. (2025). Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy. Annals of Clinical and Translational Neurology, 12(10), 2045–2055. https://doi.org/10.1002/acn3.70137
- Ibing, S., Hugo, J., Borchert, F., Schmidt, L., Benson, C., Marshall, A. A., Chasteau, C., Korie, U., Paguay, D., Sachs, J. P., Renard, B. Y., Cho, J. H., Böttinger, E. P., & Ungaro, R. C. (2025). Electronic Health Records-based identification of newly diagnosed Crohn’s Disease cases. Artificial Intelligence in Medicine, 159, 103032. https://doi.org/10.1016/j.artmed.2024.103032
- Guerrero, P., Ernebjerg, M., Holst, T., Weese, D., DiBello, H., Ibing, S., Schmidt, L., Ungaro, R., Renard, B., Lippert, C., Alleva, E., Quinn, T. D., Kovatch, P., Antao, E.-M., Heyneke, E., Rasheed, A., Kalabakov, S., Arnrich, B., Charney, A., … Nadkarni, G. (2025). The AIR·MS data platform for artificial intelligence in healthcare. JAMIA Open, 8(6), ooaf145. https://doi.org/10.1093/jamiaopen/ooaf145
- Masanneck, L., Schmidt, L., Seifert, A., Kölsche, T., Huntemann, N., Jansen, R., Mehsin, M., Bernhard, M., Meuth, S. G., Böhm, L., & Pawlitzki, M. (2024). Triage Performance Across Large Language Models, ChatGPT, and Untrained Doctors in Emergency Medicine: Comparative Study. Journal of Medical Internet Research, 26(1), e53297. https://doi.org/10.2196/53297
- Schmidt, L., Pawlitzki, M., Renard, B. Y., Meuth, S. G., & Masanneck, L. (2024). The three-year evolution of Germany’s Digital Therapeutics reimbursement program and its path forward. Npj Digital Medicine, 7(1), 1–8. https://doi.org/10.1038/s41746-024-01137-1