• Neuropsychiatry (epilepsy, neurodevelopmental disorders and related mental health disorders)
• Rare diseases and precision medicine
• Monogenic effect of rare "de novo" variants (coding and non-coding)
• Genomic data science
• Genotype-phenotype association studies in large-scale Electronic Health Records (EHRs) databases

Feel free to reach out if you are interested in a research internship or master thesis related to these topics or that requires the use of genomic data. More info on our website.

Summer Semester 

• Understanding your Genome - An Introduction to Human Genome Analysis and Interpretation

Publications

• A Eoli, S Ibing et al. A clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease. Sci Rep 14, 9642 (2024). https://doi.org/10.1038/s41598-024-59747-4 
• Z Yang et al. "Limited overlap between genetic effects on disease susceptibility and disease survival" (preprint)
• J German, M Cordioli, V Tozzo et al. Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery. Nat Med (2025). https://doi.org/10.1038/s41591-025-03645-3 

Invited talks

• Diabetes Kongress 2025, "A clustering approach to disentangle the complexity of chronic kidney disease" - Deutsche Diabetes Gesellschaft (DDG), 28th May 2025

Posters

• Poster presentation at ESHG 2024: Eoli A., Abou Jamra R., Biskup S., Gilissen C., Lemke J., Schulte B., Heyne H. "Impact of de novo variants on epilepsy in neurodevelopmental disorders".
• Poster presentation at ESHG 2022: Eoli A., Ibing S., Heyne H., Girish N., Böttinger E.P. "Use of different soft-clustering approaches to discover genetic subtypes of chronic kidney disease".