Hasso-Plattner-Institut
Prof. Dr. Christoph Lippert
  
 

Overview

N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully-functional platforms are not yet available. Here, we present the StudyU platform which includes the StudyU designer and StudyU app. With the StudyU designer, scientists are given a web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone application with innovative user-centric elements for participants to partake in the published trials and assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, as a free collaborative tool for researchers, and as a tool that can be integrated in clinical practice.

StudyU was initiated in Master project in summer 2020: “App-based N-of-1 trials in a clinically-relevant context for personalizing digital health interventions”. 

This project is embedded in different project on N-of-1 trials and digital health interventions, see here for more details.


Details

  • The StudyU platform contains the StudyU designer and the StudyU app, which allow to design and implement, and then to conduct the study, respectively.
  • You can find test versions of the StudyU designer here and of the StudyU app here.

Publications

You can find the preprint of our manuscript with a full description of StudyU here:

Konigorski S, Wernicke S, Slosarek T, Zenner AM, Strelow N, Ruether FD, Henschel F, Manaswini M, Pottbäcker F, Edelman JA, Owoyele B, Danieletto M, Golden E, Zweig M, Nadkarni G, Böttinger E (2020). StudyU: a platform for designing and conducting innovative digital N-of-1 trials. arXiv:2012.14201. https://arxiv.org/abs/2012.14201.


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