Prof. Dr. h.c. mult. Hasso Plattner
Researchers from Berlin and Brandenburg (f.l.t.r: Dr. Matthieu-P. Schapranow and Dr. Christian Regenbrecht)

Research Initiative "HANA Oncolyzer"

The research initiative "HANA Oncolyzer" was an interdisciplinary cooperation between the Charité — Universitätsmedizin Berlin, the SAP Innovation Center in Potsdam, and the Chair of Prof. Hasso Plattner at the Hasso Plattner Institute. The aim of the cooperation is to develop innovations, support the adoption of personalized medicine, and to enable a faster and improved way in treatment of patients.

Due to the overwhelming positive feedback in response to our "HANA Oncolyzer" research results that we achieved with our project partner Charité, we decided to transfer the results to the SAP Innovation Center Potsdam for building a generic software solution starting in QII/2012. In that way, we believe that our results will be soon accessible by users worldwide. As a result, researchers and physicians from various disciplines will benefit from our research on in-memory technology to analyze medical data in real time. For example, they will be able to proof hypotheses per patient individually in an interactive manner while involving all relevant patient data at a time for decision taking.

More details about features of our first innovation and a selection of latest events the HANA Oncolyzer was presented on will give you further insights into our research results.

Innovation Award 2012

The team HANA Oncolyzer was honored by the 20th Annual Innovation Award of the German Capital Region (Innovationspreis Berlin-Brandenburg) on Nov 23, 2012. We are very impressed of this unique honor. This would not be able to without a huge team and constant personal support of many people. Thus, we want to thank all of our colleagues, partners, supporters, and friends that made our visions come true!

Media Feedback


  • Hasso Plattner: SAP könnte mit Hana Erbgut analysieren (de)
  • Mit Daten gegen Krebs (de)
  • Innovationspreis Krebsforschung (de)
  • Erfolgsbeispiele: HANA Oncolyzer (de)
  • Mit Innovationspreisen ausgezeichnete Datenbank-Technologie des Hasso-Plattner-Instituts beflügelt personalisierte Krebstherapien (de)
  • Charité-Kooperation zu Medizin-Informatik erhält Innovationspreis (de)
  • Innovationspreise für Berlin und Brandenburg vergeben (de)
  • Wer sind die Finalisten des diesjährigen Innovationspreises? (de)
  • Inforadio: Innovationspreis Berlin-Brandenburg -- Das Forum mit Ute Holzhey (de)
  • Fünf Kandidaten für den Innovationspreis 2012 nominiert (de)
  • Bekanntgabe der Nominierten für Innovationspreis (de)
  • German Brew (en)
  • Biotechnologie im Aufwind (de)
  • 10. BIONNALE in Berlin – 10 Jahre Erfolgsgeschichte (de)
  • Prof. Dr. Manfred Dietel zum Hana Oncolyzer (de)
  • Prof. Dr. Ulrich Frei zum Hana Oncolyzer (de)
  • CeBIT 2012: SAP HANA on the iPad (en)(de)
  • Tagesspiegel: Angela Merkel dreht auf der Cebit ihre Runde (de)
  • DW TV: Tablet computers and apps provide a powerful tool for hospital doctors in Berlin's Charité (en)(de)
  • BioTOP: HANA Oncolyzer – a Mobile Application for Personalized Cancer Therapy (en)(de)
  • Deutschlandradio: Mobile IT zur personalisierten Krebstherapie (de)
  • SAP, Charité und HPI: Forschungsinitiative für patientenspezifische Krebstherapie (de)

HANA Oncolyzer — Innovation made in Potsdam

Charité Medicine, Charité IT, SAP's Innovation Center in Potsdam, and the Enterprise Platform and Integration Concepts (EPIC) chair at the Hasso Plattner Institute (HPI) combine their competences in the research initiative " HANA Oncolyzer" to improve the IT-aided treatment of patients suffering from cancer diseases. The improved knowledge about tumor physiognomy and about active medical ingredients will successfully support cancer treatments. As a result, cancer therapies will be more accurately adjustable for individual patients and cancer forms to improve healing evidently. "The 'heart' of our innovation builds the in-memory technology that supports the combined search in structured and unstructured medical data in real-time", says Dr. Matthieu-P. Schapranow, principal investigator of life sciences at the HPI.

The faces of the HANA Oncolyzer (f.l.t.r: Dr. Matthieu-P. Schapranow, Cafer Tosun, Dr. Christian Regenbrecht)
The faces of the HANA Oncolyzer (f.l.t.r: Dr. Matthieu-P. Schapranow, Cafer Tosun, Dr. Christian Regenbrecht)

The organizational changes in the healthcare sector require increasing support by proper IT techniques and procedures. Data needs to be available in real-time at any location — even worldwide — on mobile devices to support efforts of researchers and medical doctors. The immense increase of knowledge about cancer requires the detailed analysis of biological and genetic mutations of cancer cells to make only these harmful cells the target of future treatments and to reduce side effects. Until recently, common and unspecific therapies were applied to heal cancer. Meanwhile, treatments for specific genetic mutations are possible to support personalized medicine. "The HANA Oncolyzer highlights the potentials of the in-memory technology. It is the technical for real-time analysis of enterprise and medical data as well", says Cafer Tosun head of the SAP Innovation Center Potsdam. Research institutes and university hospital support HANA Oncolyzer by building the basis for a flexible exchange of information about efficiency of medicines and treatments. In the near future, the tumor's DNA of all cancer patients needs to be analyzed to support specific patient therapies. These analyses result in medical data in amount of multiple terabytes. "These data need to be analyzed regarding mutations and anomalies in real-time", says Dr. Christian Regenbrecht at the institute of pathology at the Charité Berlin. As one of the aims the research prototype HANA Oncolyzer was developed at our chair in cooperation with SAP's Innovation Center in Potsdam.

Learn more about the Hana Oncolyzer